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Search Results for " prmt1 in 1 "

7

Compounds

Cat No. Product Name Synonyms Targets
T38421 PRMT1-IN-1 PRMT1-IN-1
PRMT1-IN-1 is a PRMT1 inhibitor.
T10682L CARM1-IN-1 CARM1-IN-7G Histone Methyltransferase
CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.
T27133 DCLX069 DCLX 069,DCLX-069 Histone Methyltransferase
DCLX069 is a potent and selective PRMT1 inhibitor. DCLX069 occupies the SAM binding pocket to exert the inhibitory effect. DCLX069 effectively blocks cell proliferation in breast cancer, liver cancer and acute myeloid le...
T64186 CARM1-IN-1 hydrochloride
CARM1-IN-1 hydrochloride is a potent and selective inhibitor of CARM1 (IC50: 8.6 μM) with low inhibition of PRMT1 and SET7.
T27395 Furamidine dihydrochloride DB 75, DB75, NSC 305831, WR199385,Furamidine HCl
Furamidine is a cell-permeable, selective inhibitor of protein arginine methyltransferase 1 (PRMT1). Furamidine binds to strings of AT base pair sequences in DNA′s minor groove. Furamidine targets the enzyme active site ...
T81399 PRMT4-IN-2
PRMT4-IN-2 (compound 55) acts as a pan-inhibitor across various protein arginine methyltransferase (PRMT) isoforms, exhibiting inhibitory potencies with IC50 values of 92 nM for PRMT4, 436 nM for PRMT6, 460 nM for PRMT1,...
T36802 Bisubstrate Inhibitor 78
Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinam...
TargetMol